While traveling through the Himalayas, meta-mutant Charles Xavier was rescued by Nabu the Ancient One, who was Lord Supreme of Order of the Amalgam Universe at the time. Taught the mysteries of the supernatural world at the feet of the Nabu, Xavier tapped the energies of forces both telepathic and mystical, making the dour sorcerer one of the most powerful beings in the Amalgam Universe. Already a powerful meta-mutant telepath, Xavier soon surpassed his teacher and took over as Lord Supreme of Order. Though one of the founding members of the Judgment League Avengers, Dr. Strangefate moved on to more solitary pursuits in shadowy realms, leaving common protection to lesser mortals.
While a self-proclaimed protector of the universe, Doctor Strangefate was not a typical hero. He preferred to stay within his sanctum in the Tower of Strangefate and orchestrate events from a distance. He achieved his goals through manipulation of others. Super-villain Big Question got elected mayor of New Gotham City. Rumor had it that the new mayor was a mere puppet and Strangefate was his puppet-master.
